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  • Title: Effect of granulocyte colony-stimulating factor on kinetics of hemopoietic precursors in regenerating bone marrow.
    Author: Goldberg ED, Dygai AM, Zhdanov VV, Guryantseva LA, Udut EV, Popova NO, Simanina EV, Khrichkova TY.
    Journal: Bull Exp Biol Med; 2005 Jan; 139(1):154-7. PubMed ID: 16142300.
    Abstract:
    We studied processes of proliferation and differentiation of hemopoietic precursor cells in mice treated with granulocyte CSF under conditions of cytostatic myelodepression. It was found that the hemostimulating effect of original granulocyte CSF preparation consists in accelerated maturation of hemopoietic precursors and increased content of DNA-synthesizing CFU-GM in the bone marrow.
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