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  • Title: Finger-length ratios show evidence of prenatal hormone-transfer between opposite-sex twins.
    Author: van Anders SM, Vernon PA, Wilbur CJ.
    Journal: Horm Behav; 2006 Mar; 49(3):315-9. PubMed ID: 16143332.
    Abstract:
    Finger-length ratio (second to fourth finger; 2D:4D) has been associated with various measures thought to be related to prenatal androgens. In addition, hormone-transfer theory posits that hormones can transfer between twins. We examined 2D:4D in same-sex (SS) and opposite-sex (OS) dizygotic twins to test both propositions. Results show that 2D:4D is masculinized in OS females compared to SS females. This provides strong evidence that 2D:4D is laid down prenatally, and that hormones (likely androgens) can transfer from male to female fetuses. Implications for developmental timeframes for both hormone-transfer and 2D:4D are discussed.
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