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  • Title: The susceptibility of certain bacterial strains to imidazotriazine derivatives.
    Author: Sztanke K, Sidor-Wójtowicz A, Truchlińska J, Pasternak K, Sztanke M.
    Journal: Ann Univ Mariae Curie Sklodowska Med; 2004; 59(2):96-9. PubMed ID: 16146057.
    Abstract:
    The synthesized imidazo[2,1-c]triazines were tested for their antimicrobial activity. Microbiological screening tests conducted in relation to 54 strains of Gram-positive and 52 strains of Gram-negative bacteria, 6 strains of yeast-like fungi and 3 strains of moulds showed significant activity of compound 19 against 52 Gram-negative bacterial strains. This compound was active against 16 strains of Escherichia coli, 12 strains of Pseudomonas, 10 strains of Proteus spp., 8 strains of Klebsiella pneumoniae and 6 strains of Enterobacter aerogenes in the examined concentrations (100 microg ml(-1) and 200 microg ml(-1)).
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