These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Functional GABA uptake at inhibitory synapses in CA1 of chronically epileptic rats.
    Author: Stief F, Piechotta A, Gabriel S, Schmitz D, Draguhn A.
    Journal: Epilepsy Res; 2005; 66(1-3):199-202. PubMed ID: 16154723.
    Abstract:
    Inhibitory postsynaptic currents were measured in CA1 pyramidal cells from chronically epileptic rats (pilocarpine model). Tiagabine, a selective inhibitor of the GABA-uptake transporter 1 prolonged currents equally to cells from control animals. Thus, GABA-uptake has an unaltered impact on inhibitory synaptic efficacy in rats with chronic temporal lobe epilepsy, underlining the rational for the use of GABA-uptake blockers in this condition.
    [Abstract] [Full Text] [Related] [New Search]