These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Novel bioactive bromopyrrole alkaloids from the Mediterranean sponge Axinella verrucosa.
    Author: Aiello A, D'Esposito M, Fattorusso E, Menna M, Müller WE, Perović-Ottstadt S, Schröder HC.
    Journal: Bioorg Med Chem; 2006 Jan 01; 14(1):17-24. PubMed ID: 16169235.
    Abstract:
    The Mediterranean sponge Axinella verrucosa has been investigated for its alkaloid composition and has been found to produce a complex mixture of bromopyrrole alkaloids. Along with the previously isolated compounds 5-18, four novel alkaloids of this class, compounds 1-4, have been isolated, and their structures established through spectroscopic methods. Compounds 1-4 were found to display neuroprotective activity against the agonists serotonin and glutamate in vitro.
    [Abstract] [Full Text] [Related] [New Search]