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  • Title: Prenatal diagnosis of placental sulphatase deficiency.
    Author: Phillipou G, Seamark RF, Sweet R.
    Journal: Aust N Z J Obstet Gynaecol; 1979 Nov; 19(4):233-6. PubMed ID: 161704.
    Abstract:
    A gas chromatographic procedure for the quantitation of neutral steroid sulphates in maternal urine and its application to a suspected case of placental sulphatase deficiency is described. Low levels of oestriol coincident with elevated 16-hydroxylated metabolites of dehydroepiandrosterone in the maternal urine are shown to occur in this particular condition, and thus provide a convenient differentiation from fetal adrenal hypoplasia before birth.
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