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  • Title: [Stiff-person syndrome--two Hungarian cases and review of the literature].
    Author: Lengyel A, Lakos G, Sipka S, Hegedus K.
    Journal: Ideggyogy Sz; 2005 Jul 20; 58(7-8):263-72. PubMed ID: 16173274.
    Abstract:
    The stiff-man syndrome is a rare neurological disorder characterized by progressive stiffness of the axial muscles and co-contraction of agonist and antagonist muscles sometimes accompanied by involuntary sudden muscle spasms. The disease is thought to be caused by immunological changes leading to a GABA transmission disturbance, but the precise pathogenesis is not clear. Two Hungarian cases are presented in this article accompanied by a review of the literature. The aim of the paper is to call the attention on this presumably underdiagnosed disease. The diagnostic laboratory tests of the disease are available in Hungary.
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