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  • Title: A novel total synthesis of kinsenoside and goodyeroside A relying on the efficient reaction of the chiral 2(5H)-furanones.
    Author: Zhang X, Huang HH, Chen QH.
    Journal: J Asian Nat Prod Res; 2005 Oct; 7(5):711-21. PubMed ID: 16176903.
    Abstract:
    A new total synthesis of the bioactive compounds, kinsenoside and goodyeroside A, has been accomplished from readily available starting materials. The chiral 2(5H)-furanone and its enantiomer were employed as the key chiral intermediates to construct the chiral glycosides and with the appropriate stereochemistry. The spectral data of the target compounds and their acetylated derivatives and are identical with those of the natural and corresponding acetylated products.
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