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  • Title: Radiation-induced spinal cord cavernous malformation. Case report.
    Author: Yoshino M, Morita A, Shibahara J, Kirino T.
    Journal: J Neurosurg; 2005 Jan; 102(1 Suppl):101-4. PubMed ID: 16206743.
    Abstract:
    The authors report a case of a 16-year-old girl who presented with progressive gait difficulty 8 years after undergoing spinal radiation therapy for spinal astrocytoma. Magnetic resonance imaging revealed intramedullary multicentric cavity formation in the T4-10 area. Extensive subtotal resection was performed and a pathological examination of the excised tissue demonstrated cavernous malformation with radiation-induced degeneration in the surrounding vessels. This is believed to be the third case of de novo formation of an intramedullary cavernous malformation following spinal radiation therapy.
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