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  • Title: Prescribing therapy for depression: the role of learned resourcefulness, a failure to replicate.
    Author: Wetzel RD, Murphy GE, Carney RM, Whitworth P, Knesevich MA.
    Journal: Psychol Rep; 1992 Jun; 70(3 Pt 1):803-7. PubMed ID: 1620773.
    Abstract:
    Work in 1985 by Simons, Lustman, Wetzel, and Murphy showed that a patient's score on Rosenbaum's self-control scale predicted differential response to treatments for depression, with a high score predicting a good outcome with talking therapy and a low score a good outcome with drug therapy. This study of 37 patients did not replicate those findings. Using the same paradigm, we predicted response correctly 7 times and incorrectly 16 times, a clear failure. A valid method for choosing the best treatment for a patient with major depression remains to be found.
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