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  • Title: A retrospective study of hantavirus infection in Kinmen, Taiwan.
    Author: Chow L, Shu PY, Huang JH, Wang HC, Chang SF, Lu HY, Lin TH.
    Journal: J Microbiol Immunol Infect; 2005 Oct; 38(5):343-9. PubMed ID: 16211143.
    Abstract:
    In this retrospective study, 140 serum samples collected from 85 scrub typhus-negative patients in Kinmen Island in 2000 were tested for antibodies to hantavirus using enzyme-linked immunosorbent assay. Seven patients (8.23%) were confirmed as having hantavirus infection as demonstrated by increased hantavirus-specific immunoglobulin M and/or immunoglobulin G antibodies in their convalescent serum samples. Analysis of indirect immunofluorescence assay showed that Seoul type was the etiologic agent. Serosurvey of rodents caught in the resident township of these hantavirus-infected human cases showed that the seroprevalence of antibodies to hantavirus among Rattus norvegicus, Mus musculus, and R. flavipectus was 50% (4/8), 20% (1/5), and 2% (7/348), respectively. Molecular analysis showed that these reservoir hosts carried a Seoul type hantavirus. To our knowledge, this is the first report demonstrating indigenous hantavirus cases in Kinmen.
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