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  • Title: Molecular characteristics of cockroach allergens.
    Author: Wu CH, Lee MF.
    Journal: Cell Mol Immunol; 2005 Jun; 2(3):177-80. PubMed ID: 16212884.
    Abstract:
    Cockroaches, commonly found in urban dwellings worldwide, have long been considered vectors of various infectious diseases and cockroach allergens are one of the major etiologic risk factors for IgE-mediated allergic respiratory illness throughout the world. A high prevalence of cockroach hypersensitivity in atopic (20-55%) and asthmatic (49-60%) populations has been documented. Cockroach allergens with molecular weights ranging from 6 to 120 kD have been identified by various standard immunochemical techniques. This article covers the characteristics of major cockroach allergens that have been purified, sequenced, cloned, and produced as recombinant proteins.
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