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  • Title: Protozoan programmed cell death--insights from Blastocystis deathstyles.
    Author: Tan KS, Nasirudeen AM.
    Journal: Trends Parasitol; 2005 Dec; 21(12):547-50. PubMed ID: 16223601.
    Abstract:
    Programmed cell death (PCD) is an essential process in the growth and development of multicellular organisms. However, accumulating evidence indicates that unicellular eukaryotes can also undergo PCD with apoptosis-like features. The protozoan parasite Blastocystis hominis has been reported to exhibit both apoptotic and non-apoptotic features of PCD when exposed to a variety of stimuli. Recent observations of PCD pathways in Blastocystis suggest that this protozoan, as is the case with its multicellular counterparts, possesses complex cell-death mechanisms.
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