These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Comparative simulations of aquaporin family: AQP1, AQPZ, AQP0 and GlpF.
    Author: Hashido M, Ikeguchi M, Kidera A.
    Journal: FEBS Lett; 2005 Oct 24; 579(25):5549-52. PubMed ID: 16225876.
    Abstract:
    Molecular dynamics simulations were performed for four members of the aquaporin family (AQP1, AQPZ, AQP0, and GlpF) in the explicit membrane environment. The single-channel water permeability, pf, was evaluated to be GlpF approximately AQPZ > AQP1 >> AQP0, while their relative pore sizes were GlpF >> AQP1 > AQPZ >> AQP0. This relation between pf and pore size indicates that water permeability was determined not only by the channel radius, but also another competing factor. Analysis of water dynamics revealed that this factor was the single-file nature of water transport.
    [Abstract] [Full Text] [Related] [New Search]