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  • Title: [Baboon syndrome due to a polysensitization with corticosteroids].
    Author: Armingaud P, Martin L, Wierzbicka E, Estève E.
    Journal: Ann Dermatol Venereol; 2005; 132(8-9 Pt 1):675-7. PubMed ID: 16230917.
    Abstract:
    BACKGROUND: The Baboon syndrome is a form of systemic contact dermatitis. We report the case of a patient who presented a Baboon syndrom following oral medication with betamethasone. CASE REPORT: A 58 year-old man had consulted for eczema involving the groin, the buttocks and the axillae. It was clinically a baboon syndrome related to oral betamethasone (Celestene) treatment, ingested 48 hours earlier. The exploration with a patch-test confirmed the sensitization to betamethasone. This exploration also showed a sensitization to all four classes of corticosteroids. Prolonged withdrawal of all corticosteroids led to the clear improvement of his eczema. DISCUSSION: The baboon syndrome of this patient was the symptom of a systemic eczema due to betamethasone. The patient was sensitized by the percutaneous route. The application of many topical corticosteroids had provoked this polysensitization. It was impossible to consider a safe corticosteroid for this patient.
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