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  • Title: Expression of the immediate-early gene cFos in brain of the rats exposed to repeated 2 G influence.
    Author: Fidelina OV, Krasnov IB.
    Journal: J Gravit Physiol; 2004 Jul; 11(2):P35-6. PubMed ID: 16231445.
    Abstract:
    Early gene c-Fos expression was studied by means of c-Fos protein immunostaining in brain locus coeruleus (LC) of the rats exposed to primary and repeated hypergravity. One-hour 2 G influence on rats induced in LC cells expression of c-Fos protein, pointing out early gene c-Fos expression and synaptic activation of LC neurons. After repeated 1-hour 2 G, postponed for 35 days after primary 30-day 2 G influence, expression of c-Fos protein in LC neurons was not found. This fact is considered as a sign of memorizing of primary hypergravity influence.
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