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  • Title: Transition of mechanical property of porous alginate scaffold with cells during culture period.
    Author: Sakai S, Masuhara H, Yamada Y, Ono T, Ijima H, Kawakami K.
    Journal: J Biosci Bioeng; 2005 Jul; 100(1):127-9. PubMed ID: 16233864.
    Abstract:
    The rupture forces of porous alginate scaffolds seeded with hepatocytes or fibroblast-like cells increased during 3 d of culture and then decreased. The phenomenon was independent of the number of viable cells within the scaffolds, but dependent on protein adsorption to the alginate as well as a reduction in the degree of crosslinks of the calcium-alginate gel.
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