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  • Title: An open study of botulinum-A toxin treatment of trigeminal neuralgia.
    Author: Piovesan EJ, Teive HG, Kowacs PA, Della Coletta MV, Werneck LC, Silberstein SD.
    Journal: Neurology; 2005 Oct 25; 65(8):1306-8. PubMed ID: 16247065.
    Abstract:
    Thirteen subjects with trigeminal neuralgia were treated with botulinum-A neurotoxin (BoNT/A) in an open-label pilot study. After BoNT/A, visual analog scale score, surface area of pain, and therapeutic coefficient were reduced in all patients and for all branch trigeminal nerves studied. Therefore, BoNT/A is an efficient treatment. There were no major side effects. A placebo-controlled clinical trial is needed to confirm these findings.
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