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Title: Diffuse leptomeningeal involvement by a ganglioglioma in a child. Case report. Author: Wacker MR, Cogen PH, Etzell JE, Daneshvar L, Davis RL, Prados MD. Journal: J Neurosurg; 1992 Aug; 77(2):302-6. PubMed ID: 1625019. Abstract: Gangliogliomas are tumors composed of neuronal and glial elements that typically grow slowly by expansion only. This report describes a 20-month-old girl with a ganglioglioma that extensively involved the subarachnoid space; microscopic foci of tumor were found in the brain and spinal cord. Despite chemotherapy and radiation therapy, the child died 5 months after diagnosis. Molecular genetic analysis showed loss of chromosome 17p DNA sequences in the tumor tissue.[Abstract] [Full Text] [Related] [New Search]