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  • Title: Serum soluble transferrin receptor is a valuable diagnostic tool in iron deficiency of breath-holding spells.
    Author: Handan U, Sükrü C, Gülhis D, Hafize G, Atilla EH, Nejat A.
    Journal: Pediatr Hematol Oncol; 2005 Dec; 22(8):711-6. PubMed ID: 16251178.
    Abstract:
    Iron-deficiency anemia may be a factor contributing to breath-holding spells. The serum transferrin receptor provides a useful measure of tissue iron deficiency. In this study of 50 breath-holders, while iron-deficiency anemia was detected in 28 (56%) of patients with routine tests, serum transferrin receptor levels were found increased in all patients. A positive correlation was detected between serum soluble transferrin receptor levels and frequency of attacks. It is suggested that the serum transferrin receptor level is useful as a single test for identification of iron deficiency in breath-holders. Moreover, if iron deficiency can be diagnosed earlier, then patients can be treated earlier.
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