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  • Title: Improvement of oligoasthenozoospermia in epileptic patients on switching anti-epilepsy medication from sodium valproate to phenytoin.
    Author: Hayashi T, Yoshida S, Yoshinaga A, Ohno R, Ishii N, Yamada T.
    Journal: Scand J Urol Nephrol; 2005; 39(5):431-2. PubMed ID: 16257847.
    Abstract:
    We present two cases of infertile male patients with oligoasthenozoospermia who were receiving anti-epilepsy medication. Complete reversal of the spermatic dysfunction followed by a successful conception was achieved after discontinuation of sodium valproate, suggesting that the drug was responsible for spermatic dysfunction in these individuals.
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