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  • Title: Surgical treatment and outcome of conventional pelvic chondrosarcoma.
    Author: Donati D, El Ghoneimy A, Bertoni F, Di Bella C, Mercuri M.
    Journal: J Bone Joint Surg Br; 2005 Nov; 87(11):1527-30. PubMed ID: 16260673.
    Abstract:
    We reviewed 124 patients with a conventional pelvic chondrosarcoma who had been treated over a period of 20 years. We recorded the type of tumour (central or peripheral), type of operation (limb salvage surgery or hemipelvectomy), the grade of tumour, local recurrence and/or metastases, in order to identify the factors which might influence survival. More satisfactory surgical margins were achieved for central tumours or in those patients treated by hemipelvectomy. However, grade 1 tumours, whatever the course, did not develop metastases or cause death, while grade 3 tumours had the worst outcome and prognosis. Central, high-grade tumours require aggressive surgical treatment in order to achieve adequate surgical margins, particularly in those lesions located close to the sacroiliac joint. By contrast, grade 1 peripheral chondrosarcomas may be treated with contaminated margins in order to reduce operative morbidity, but without reducing survival.
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