These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Fibroblast growth factor (FGF)-23 in patients with hypoparathyroidism].
    Author: Yamashita H, Noguchi S, Yamasaki Y, Hasegawa H, Yamashita T, Fukumoto S, Shigematsu T, Kazama J, Fukagawa M.
    Journal: Clin Calcium; 2005 Sep; 15 Suppl 1():41-5; discussion 45. PubMed ID: 16272628.
    Abstract:
    Hypoparathyroidism is a well-described cause of hyperphosphatemia. We aimed to clarify the physiological role of FGF-23 in serum phosphate homeostasis in hypoparathyroidism after thyroidectomy. Increased serum FGF-23 levels were found in patients with hyperphosphatemia and hypocalcemia, caused by hypoparathyroidism after thyroidectomy. After the recovery of parathyroid function, the serum level of calcium, phosphate, and FGF-23 was normalized. Serum FGF-23 levels were significantly higher in patients with permanent hypoparathyroidism than in healthy controls. These results indicate that FGF-23 may play an important role in serum phosphate homeostasis by its up-regulation in the hyperphosphatemic condition.
    [Abstract] [Full Text] [Related] [New Search]