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  • Title: Glucose biosensor based on Au nanoparticles-conductive polyaniline nanocomposite.
    Author: Xian Y, Hu Y, Liu F, Xian Y, Wang H, Jin L.
    Journal: Biosens Bioelectron; 2006 Apr 15; 21(10):1996-2000. PubMed ID: 16275055.
    Abstract:
    In this paper, we report a novel glucose biosensor based on composite of Au nanoparticles (NPs)-conductive polyaniline (PANI) nanofibers. Immobilized with glucose oxidase (GOx) and Nafion on the surface of nanocomposite, a sensitive and selective biosensor for glucose was successfully developed by electrochemical oxidation of H2O2. The glucose biosensor shows a linear calibration curve over the range from 1.0x10(-6) to 8.0x10(-4) mol/L, with a slope and detection limit (S/N=3) of 2.3 mA/M and 5.0x10(-7) M, respectively. In addition, the glucose biosensor system indicates excellent reproducibility (less than 5% R.S.D.) and good operational stability (over 2 weeks).
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