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  • Title: Parthenogenic origin of benign ovarian teratomas.
    Author: Linder D, McCaw BK, Hecht F.
    Journal: N Engl J Med; 1975 Jan 09; 292(2):63-6. PubMed ID: 162806.
    Abstract:
    To determine the origin of benign cystic teratomas of the ovary, chromosome-banding studies were done on normal tissues and teratomas from five patients. The normal tissues were heterozygous (+/-) for 17 chromosome polymorphisms at or near the centromere, whereas the teratomas were uniformly homozygous (+/+ or -/-). These findings and those employing electrophoretic variants indicate that ovarian teratomas are parthenogenic tumors that arise from a single germ cell after the first meiotic division.
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