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  • Title: Management of delayed intracranial and intraspinal metastases of intradural spinal paragangliomas.
    Author: Thines L, Lejeune JP, Ruchoux MM, Assaker R.
    Journal: Acta Neurochir (Wien); 2006 Jan; 148(1):63-6; discussion 66. PubMed ID: 16283104.
    Abstract:
    The preferential site of extra-adrenal paragangliomas is the head and neck region. However intradural spinal paragangliomas are commonly described and are considered as benign entities. We report the case of a paraganglioma of the cauda equina followed after complete surgical removal by intracranial and intraspinal cerebrospinal fluid metastases. Seven years after the first operation, a cystic cerebellar lesion was successfully treated by surgery. During a long follow-up, four locations in the posterior fossa, a lumbar recurrence and metastatic nodules at T6 and S1-S2 level were also discovered. Radiotherapy stopped the lesions' growth and allowed improvement of the neurological status. Through a review and analysis of the literature, we discuss the management of this unusual evolution.
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