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  • Title: Histopathologic aspects of the limited endometrial hyperplasias--a study concerning 149 cases.
    Author: Simionescu C, Florescu M, Niculescu M, Bălă S, Manea M.
    Journal: Rom J Morphol Embryol; 2005; 46(1):51-5. PubMed ID: 16286985.
    Abstract:
    This study concerns 147 cases of limited endometrial hyperplasia, diagnosed at patients between IV, V, VI and VII decades of life. Histopathologically, the aspects were of basal hyperplasia--40 cases and polyp hyperplasia--107 cases. The polyp-like hyperplasia was present at pre and postmenopausal patients. At the premenopausal patients the polyps were hormonally active: glandular, glandular-cystic and adenomatous type polyps. In contrast, the majority of the postmenopausal patients presented hormonally inactive polyps, like cystic atrophic or fibrous polyps. Modifying the prognosis of lesions, we took in consideration the morphologic changes associated with these lesions, like epithelial metaplasia or nuclear atypia.
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