These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Acid acclimation by Helicobacter pylori.
    Author: Sachs G, Weeks DL, Wen Y, Marcus EA, Scott DR, Melchers K.
    Journal: Physiology (Bethesda); 2005 Dec; 20():429-38. PubMed ID: 16287992.
    Abstract:
    Helicobacter pylori is a Gram-negative neutralophile associated with peptic ulcers and gastric cancer. It has a unique ability to colonize the human stomach by acid acclimation. It uses the pH-gated urea channel, UreI, to enhance urea access to intrabacterial urease and a membrane-anchored periplasmic carbonic anhydrase to regulate periplasmic pH to approximately 6.1 in acidic media, whereas other neutralophiles cannot regulate periplasmic pH and thus only transit the stomach.
    [Abstract] [Full Text] [Related] [New Search]