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  • Title: Growth, morbidity and mortality after chickenpox infection in young children in Guinea-Bissau.
    Author: Poulsen A, Cabral F, Nielsen J, Roth A, Lisse I, Aaby P.
    Journal: J Infect; 2005 Nov; 51(4):307-13. PubMed ID: 16291283.
    Abstract:
    OBJECTIVE: To examine whether chickenpox in children below 2 years of age is associated with post-infection changes in growth, morbidity or mortality. METHODS: An outbreak of chickenpox was investigated in Guinea-Bissau. An examination, interview and anthropometry were performed 6 months after the epidemic for a group of children and matched controls whose weight had been measured at the time of the chickenpox episode. All children diagnosed with chickenpox before 2 years of age were followed for survival and hospitalisations to the age of 3 years and compared with all other children in the community. RESULTS: At the 6-month follow-up, skin infections tended to be more frequent in cases (p<0.06) and more cases had used antibiotics within the last month (p<0.03). Although there had been no difference before chickenpox infection, girls with chickenpox infection had significantly higher weight, height and larger arm-circumferences than controls (all p<0.01). After chickenpox infection, the incidence of hospitalisation and long-term mortality was the same for cases and other children in the community (respectively, incidence rate ratio=1.16 (0.77-1.74) and mortality ratio=0.74 (0.39-1.41)). CONCLUSION: Though chickenpox may be associated with increased short-term morbidity, it does not appear to have any negative long-term effect on growth, severe morbidity and survival of young children.
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