These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The roles of orphan nuclear receptors in the development and function of the immune system.
    Author: Dzhagalov I, Zhang N, He YW.
    Journal: Cell Mol Immunol; 2004 Dec; 1(6):401-7. PubMed ID: 16293208.
    Abstract:
    Hormones and their receptors regulate cell growth, differentiation and apoptosis and also play important roles in immune function. Recent studies on the subfamily of the orphan nuclear receptors known as retinoid-acid related orphan receptors (ROR) have shed important insights on the roles of this group of nuclear proteins in the development and function of the immune system. RORalpha regulates inflammatory cytokine production in both innate and adaptive immune system while RORgamma regulates the normal development of T lymphocyte repertoire and secondary lymphoid organs.
    [Abstract] [Full Text] [Related] [New Search]