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  • Title: Acute tumor lysis syndrome induced by rituximab in diffuse large B-cell lymphoma.
    Author: Jabr FI.
    Journal: Int J Hematol; 2005 Nov; 82(4):312-4. PubMed ID: 16298821.
    Abstract:
    Acute tumor lysis syndrome (ATLS) is a well-known complication of chemotherapy in patients with rapidly proliferative hematopoietic malignancies such as lymphoma and leukemia. Rituximab anti-CD20 monoclonal antibody, an alternative to chemotherapy in the treatment of low-grade follicular lymphoma, also has been associated with ATLS. Rituximab-induced ATLS has been reported in 2 patients with chronic lymphocytic leukemia and in 2 patients with non-Hodgkin's lymphoma. I report another case of rituximab-induced ATLS in a patient with diffuse large B-cell lymphoma and review the cases in the literature.
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