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  • Title: Local axon guidance in cerebral cortex and thalamus: are we there yet?
    Author: Grove EA.
    Journal: Neuron; 2005 Nov 23; 48(4):522-4. PubMed ID: 16301165.
    Abstract:
    Normal brain function requires the development of precise connections between thalamus and cerebral cortex. In this issue of Neuron, Cang et al. and Tori and Levitt argue that EphA/ephrin-A signaling in the target tissue guides sensory thalamic axons to the correct cortical area, and sensory cortical axons to precise thalamic targets. Although EphA/ephrin-A signaling organizes sensory maps within areas, and thalamocortical axons in the internal capsule, both papers argue that each developmental event is dissociable from the others.
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