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  • Title: [Wegener's granulomatosis: a report of 6 patients].
    Author: Tural C, Cuxart A, Bertrán X, Puigdengoles X, Segura A, Rey-Joly C.
    Journal: Med Clin (Barc); 1992 Jun 06; 99(2):63-6. PubMed ID: 1630183.
    Abstract:
    The clinical and analytical manifestations and the evaluation of 6 patients diagnosed with Wegener's granulomatosis (WG) in the Germans Trias i Pujol Hospital between 1986-1990 are described. The most frequent clinical manifestation found were general and respiratory symptoms. Three patients presented an alteration in renal function and urinary sedimentation. Antibodies against the cytoplasm of the neutrophils (ANCA) detected by indirect immunofluorescence (IIF) were positive in 4 patients. All the patients underwent initial complete remission with immunodepressor treatment and one presented relapse of the disease at 19 months of diagnosis. Complications were: opportunistic infections obliging discontinuation of treatment in one patient, distal necrosis of the fingers requiring amputation in another patient and massive atelectasis of the right lung requiring pneumonectomy in a third patient.
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