These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Effects of endurance training on myosin heavy-chain isoforms and enzyme activity in the rat diaphragm.
    Author: Sugiura T, Morimoto A, Murakami N.
    Journal: Pflugers Arch; 1992 May; 421(1):77-81. PubMed ID: 1630886.
    Abstract:
    We investigated the effects of endurance training (20 m/min, 60 min/day, 5 days/week) on myosin heavy-chain (MHC) isoforms and succinic dehydrogenase (SDH) activity in rat crural and costal diaphragms, and plantaris muscles. Although the 4-week endurance training produced significant (P less than 0.05) increases, both in SDH activity and the percentage of isoform HCIIa in the plantaris of the trained rat compared with the sedentary control rat, these alterations did not occur in either the crural or costal diaphragms. After 10 weeks of endurance training, trained animals had significantly (P less than 0.05) higher SDH activity in the costal diaphragm and the plantaris. Moreover, a significant (P less than 0.05) decrease occurred in the percentage of HCIIb in the costal diaphragm, and a significant (P less than 0.01) decrease in the percentage of HCIIb concomitant with a significant (P less than 0.05) increase of HCIIa resulted in the plantaris. However, the crural diaphragm did not show any significant changes after 10 weeks of endurance training. These results indicate that endurance training induces an alteration in the expression of an MHC phenotype, in addition to causing an increase in oxidative enzyme activity. However, the alterations in response to endurance training are apparently not uniform, varying between regions and/or kinds of muscles.
    [Abstract] [Full Text] [Related] [New Search]