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  • Title: Meroditerpenoids from a Formosan soft coral Nephthea chabrolii.
    Author: Su JH, Ahmed AF, Sung PJ, Wu YC, Sheu JH.
    Journal: J Nat Prod; 2005 Nov; 68(11):1651-5. PubMed ID: 16309317.
    Abstract:
    Eight new meroditerpenoid-related metabolites, including one naphthoquinone derivative, chabrolonaphthoquinone B (1), four tetraprenyltoluquinone-related compounds, chabrolobenzoquinones E-H (2-5), and three tetraprenyltoluquinol-related metabolites, chabrolohydroxybenzoquinones E-G (6-8), were isolated from the organic extract of a Taiwanese soft coral Nephthea chabrolii. The structures of 1-8 were elucidated on the basis of extensive spectroscopic analysis and by comparison of the data with those of the related metabolites. Cytotoxic activity of metabolites 1-3 and 5-8 against a limited panel of cancer cell lines is also described.
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