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  • Title: [Breast adenocarcinoma: critical analysis of sentinel lymph node histopathological results of 542 procedures].
    Author: Baranzelli MC, Giard S, Cabaret V, Chauvet MP, Robin YM, Vilain MO, Carpentier P, Belkacémi Y, Bonneterre J.
    Journal: Bull Cancer; 2005 Nov; 92(11):983-7. PubMed ID: 16316832.
    Abstract:
    Between February 2001 and March 2003, 542 sentinel lymph node procedures were performed for localised breast carcinoma (T0-T1, N0, M0) without any previous treatment. Frozen sections were performed in 515 cases and they did not reveal metastases in 446 cases. Fifty-two micrometastases < 2 mm and 18 macrometastases were reported by definitive histopathological exam. Axillary clearance was performed in 50/70 patients (38 with micrometastases and 12 for macrometastases). Modalities of histopathological procedure are discussed and particularly number and interval of serial slides with or without immunochemistry ; 81.8% (36/44) of micrometastases were detected on the two first serial sections. Decisional value of axillary clearance performed in case of micrometastases is also evaluated.
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