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  • Title: [Quality assurance of results of clinical chemical analyses in Danish hospital laboratories].
    Author: Raabo E, Bartels PD, Blom M, Christensen NJ, Hansen MS, Jørgensen PJ, Olsen JS, Petersen AW, Uldall A.
    Journal: Ugeskr Laeger; 1992 Jun 01; 154(23):1627-31. PubMed ID: 1631996.
    Abstract:
    During the past 35 years, voluntary professional assessment of quality of the results of analyses in Danish hospital laboratories has been undertaken under the auspices of the Danish Society of Clinical Chemistry. The analytical quality of the laboratories is described by their "imprecision" and "accuracy" as expressed by "coefficient of variation" and "bias", respectively. The participation in these programmes was 90%. During the period between 1968 and 1987, inter-laboratory variation decreased markedly where all analyses were concerned. To ensure the necessary and adequate quality, establishment of specifications of quality based on clinical/biological goals of quality has proved necessary. The commonest reasons for large imprecision and bias from the target values are less specific methods of analysis, errors in calibration and sporadic "outliers". As the result of a stable organisation for ensuring quality, Denmark is well equipped for the introduction of the great demands in documentation of quality which may be anticipated from the Common Market during the immediate future.
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