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  • Title: Concise synthesis of pochonin A, an HSP90 inhibitor.
    Author: Moulin E, Barluenga S, Winssinger N.
    Journal: Org Lett; 2005 Dec 08; 7(25):5637-9. PubMed ID: 16321010.
    Abstract:
    [chemical reaction: see text]. An expedient synthesis of (-)-pochonin A is reported (seven steps). This natural product is closely related to radicicol and was shown to be a 90 nM inhibitor of HSP90.
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