These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Growth hormone therapy in achondroplasia.
    Author: Horton WA, Hecht JT, Hood OJ, Marshall RN, Moore WV, Hollowell JG.
    Journal: Am J Med Genet; 1992 Mar 01; 42(5):667-70. PubMed ID: 1632435.
    Abstract:
    A pilot study was carried out to examine the safety and efficacy of recombinant human growth hormone for growth-promoting therapy of achondroplasia. The data suggest that the agent in doses used to treat non-GH-deficient forms of short stature (0.3 mg/kg/wk) modestly increases overall height velocity in some children with achondroplasia. The effect was seen mainly in children with the lowest growth velocities prior to treatment. No untoward effects were noted. Several questions were raised that require further study.
    [Abstract] [Full Text] [Related] [New Search]