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  • Title: Intravascular thermographic assessment in human coronary atherosclerotic plaques by a novel flow-occluding sensing catheter: a safety and feasibility study.
    Author: Belardi JA, Albertal M, Cura FA, Mendiz O, Balino PP, Padilla LT, Lauer M, Korotko J, O'Neill W.
    Journal: J Invasive Cardiol; 2005 Dec; 17(12):663-6. PubMed ID: 16327050.
    Abstract:
    OBJECTIVE: To report the safety and feasibility of a new occluding thermographic catheter in patients with coronary artery disease. BACKGROUND: Although plaque temperature heterogeneity is shown in atheromatous plaques, significant underestimation is encountered due to the cooling effect of the uninterrupted blood flow. METHODS: The catheter was positioned at the stenotic site. Blood flow was interrupted by an expandable braid located at the distal portion of the catheter. Then, thermographic assessment was performed. RESULTS: In one patient, the catheter could not reach the lesion due to tortuosity. Of the 20 lesions evaluated, 5 were excluded due to unsuccessful interruption of blood flow. We identified 5 lesions with a 0.3 degrees Celcius elevations compared to the same site without interruption of blood flow. There were no procedural complications. CONCLUSION: The new catheter-occluding thermographic device, while avoiding the blood flow cooling effect, appears to be safe and feasible for the assessment of human plaque temperature heterogeneity.
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