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  • Title: [Quality of life in restless legs syndrome. Influence of daytime sleepiness and fatigue].
    Author: Gerhard R, Bosse A, Uzun D, Orth M, Kotterba S.
    Journal: Med Klin (Munich); 2005 Nov 15; 100(11):704-9. PubMed ID: 16328177.
    Abstract:
    BACKGROUND AND PURPOSE: Restless legs syndrome (RLS) is a frequent neurologic disorder characterized by leg paresthesia and motor restlessness. It is still under debate to which amount the disease affects quality of life as it causes daytime sleepiness and fatigue. The presented study evaluates the daytime problems by different scales. PATIENTS AND METHODS: 28 patients (19 women, nine men, aged 58.6 +/- 11.9 years) with RLS (78% with a severe form) were evaluated with the Epworth Sleepiness Scale (ESS), the Fatigue Severity Scale (FSS) and the SF-36 to judge quality of life. Subscales of the SF-36 contain either rather physical or mental components. RESULTS: 17/28 patients showed an increased daytime sleepiness (ESS) and 17/28 increased fatigue (FSS), whereby these symptoms did not correlate. With regard to the SF-36 scores higher values of fatigue caused a greater limitation of the physical health, daytime sleepiness correlated with limitation of the mental health. CONCLUSION: The study clearly demonstrates an impairment by fatigue and daytime sleepiness in RLS patients. Daytime symptoms worsen quality of life. Different scales have to be used to measure the different daytime symptoms. Therapy must be adjusted to the leading symptoms (e. g., stimulants in daytime sleepiness).
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