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  • Title: Blue rubber-bleb nevus syndrome: report of a case associated with osteoid osteomas.
    Author: Palleschi GM, Torchia D, Fabbri P.
    Journal: J Dermatol; 2005 Jul; 32(7):589-93. PubMed ID: 16335877.
    Abstract:
    Blue rubber-bleb nevus syndrome (BRBNS), or Bean's syndrome, is a rare angiomatosis characterized by multiple cavernous hemangiomas of the skin, mucosae and frequently of other sites. A 49-year-old male patient had been affected since birth by multiple angiomas localized in the skin, lips, oral cavity, cranial theca, and central nervous system; intrauterine rupture of angiomas in the right parietal lobe had caused partial hypotrophic paralysis of the left hemisoma. In addition to BRBNS, the patient was affected by three osteoid osteomas: this never-described clinical association is here discussed.
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