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  • Title: Coxiella burnetii vascular graft infection.
    Author: Senn L, Franciolli M, Raoult D, Moulin A, Von Segesser L, Calandra T, Greub G.
    Journal: BMC Infect Dis; 2005 Dec 07; 5():109. PubMed ID: 16336642.
    Abstract:
    BACKGROUND: Coxiella burnetii, the causative agent of Q fever, may cause culture-negative vascular graft infections. Very few cases of C. burnetii infection of a vascular graft have been reported. All were diagnosed by serology. CASE PRESENTATION: We report the first case of Coxiella burnetii vascular graft infection diagnosed by broad-range PCR and discuss the diagnostic approaches and treatment strategies of chronic C. burnetii infection. CONCLUSION: C. burnetii should be considered as etiological agent in patients with a vascular graft and fever, abdominal pain, and laboratory signs of inflammation, with or without exposure history. Broad-range PCR should be performed on culture-negative surgical samples in patients with suspected infection of vascular graft.
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