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  • Title: Effective detergent/lipid ratios in the solubilization of phosphatidylcholine vesicles by Triton X-100.
    Author: Partearroyo MA, Urbaneja MA, Goñi FM.
    Journal: FEBS Lett; 1992 May 11; 302(2):138-40. PubMed ID: 1633845.
    Abstract:
    Effective detergent:lipid ratios (i.e. molar ratios in the mixed aggregates, vesicles or micelles) have been estimated for the solubilization of phosphatidylcholine vesicles by Triton X-100. Effective molar ratios are given for both the onset and the completion of bilayer solubilization; small unilamellar, large unilamellar and multilamellar vesicles have been used. Effective detergent:lipid ratios are independent of phospholipid concentration, and their use allows a deeper understanding of membrane-surfactant interactions.
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