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  • Title: [The relationship between skin test results and serum eosinophilic cationic protein, nasal eosinophilia, and total IgE values in patients with allergic rhinitis].
    Author: Pinar E, Bolat F, Oncel S, Köseoğlu M, Yüksel H, Calli C.
    Journal: Kulak Burun Bogaz Ihtis Derg; 2005; 14(5-6):101-5. PubMed ID: 16340277.
    Abstract:
    OBJECTIVES: We investigated the relationship between positive skin test results and serum eosinophilic cationic protein (ECP), nasal eosinophilia, and total IgE levels in patients with allergic rhinitis. PATIENTS AND METHODS: The study included 36 patients with allergic rhinitis (26 females, 10 males; mean age 32.8 years; range 17 to 60 years) and with a positive skin test result. Serum ECP, nasal eosinophilia, and serum total IgE levels were assessed and compared with a control group of 18 healthy volunteers (15 females, 3 males; mean age 30.3 years; range 20 to 49 years) and correlation was sought with skin test results. RESULTS: Twenty-five patients were sensitive to only seasonal, four patients to only perennial, and seven patients to both seasonal and perennial allergens. Twelve patients were sensitive to one allergen, seven patients to two, and 17 patients to three or more allergens. Compared to controls, the mean serum ECP, nasal eosinophilia, and serum total IgE values were significantly higher in the patient group (p<0.05). These parameters did not show significant relationship with the type and number of allergens (p>0.05). CONCLUSION: Serum ECP, nasal eosinophilia, and serum total IgE levels increase in patients with allergic rhinitis. These parameters are not affected by sensitivity to seasonal or perennial allergens.
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