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  • Title: Successful treatment of a hepatic cyst by one-shot instillation of minocycline chloride.
    Author: Hagiwara H, Kasahara A, Hayashi N, Kono M, Suzuki K, Kashio S, Fusamoto H, Kamada T.
    Journal: Gastroenterology; 1992 Aug; 103(2):675-7. PubMed ID: 1634083.
    Abstract:
    Hepatic cysts are not rare but usually are asymptomatic; however, large ones sometimes show clinical manifestations. Treatment of a solitary hepatic cyst by one-shot instillation of minocycline chloride is reported here; 500 mg of minocycline chloride was instilled into the hepatic cyst, 11 cm in diameter, through a percutaneous transhepatic cholangiography needle under ultrasound guidance. After 5 weeks, the cyst had decreased in size to 5 cm. Five months later, the cyst could not be detected by diagnostic imaging. Fifteen months after the treatment, no reaccumulated fluid was observed. Ultrasound-guided percutaneous one-shot instillation of minocycline chloride seems to be a safe, easy, and useful procedure for treating a hepatic cyst.
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