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Title: Prolactin receptors in rat liver: possible induction by prolactin. Author: Posner BI, Kelly PA, Friesen HG. Journal: Science; 1975 Apr 04; 188(4183):57-9. PubMed ID: 163493. Abstract: A prolactin receptor, present in adult female rat liver, can be induced in males by estrogen. Hypophysectomy diminished receptor levels in the female and rendered males unresponsive to estrogen. A renal pituitary implant blunted the decrease in hypophysectomized females and induced the receptor in hyophysectomized males. The increased receptor level in hypophysectomized males with a renal pituitary implant was preceded by a sustained elevation of circulating prolactin. Our observations suggest that prolactin induces its own receptor.[Abstract] [Full Text] [Related] [New Search]