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  • Title: Antibacterial and antitumor macrolides from Streptomyces sp. Is9131.
    Author: Zhao PJ, Fan LM, Li GH, Zhu N, Shen YM.
    Journal: Arch Pharm Res; 2005 Nov; 28(11):1228-32. PubMed ID: 16350846.
    Abstract:
    Four compounds, including two novel macrolides, were isolated from an endophyte Streptomyces sp. Is9131 of Maytenus hookeri. Spectral data indicated that these compounds were dimeric dinactin (1), dimeric nonactin (2), cyclo-homononactic acid (3), and cyclo-nonactic acid (4). Bioassay results showed that dimeric dinactin had strong antineoplastic activity and antibacterial activity.
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