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  • Title: Effect of sucrose concentration on dental biofilm formed in situ and on enamel demineralization.
    Author: Aires CP, Tabchoury CP, Del Bel Cury AA, Koo H, Cury JA.
    Journal: Caries Res; 2006; 40(1):28-32. PubMed ID: 16352877.
    Abstract:
    The relationship between sucrose concentration and cariogenic potential was studied in situ. Adult volunteers wore intraoral palatal appliances containing human dental enamel blocks, which were extraorally submitted 8 times a day for 14 days, to the treatments: deionized distilled water and sucrose solutions from 1 to 40%. The biofilm formed was analyzed with respect to acidogenicity and biochemical composition; enamel demineralization was evaluated by microhardness. The results showed that 1% sucrose is less cariogenic than 5% or higher concentrations, although sucrose solution at 40% was still able to increase the concentration of insoluble polysaccharide in the biofilm formed. The findings suggest that the threshold of sucrose solution concentration for the formation of a cariogenic biofilm is 5%, which provided the same cariogenic potential as that observed for 10 and 20% sucrose solution.
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