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  • Title: [Expression of HLA-G protein in trophoblast cells].
    Author: Wang YQ, Chen SL, Xing FQ.
    Journal: Di Yi Jun Yi Da Xue Xue Bao; 2005 Dec; 25(12):1488-90. PubMed ID: 16354612.
    Abstract:
    OBJECTIVE: To investigate the expression of human leucocyte antigen protein G (HLA-G) in different trophoblast cells and different stages of pregnancy. METHODS: The expression of HLA-G protein in normal placenta and trophoblasts of different trimesters was detected using immunohistochemical method (SP). RESULTS: HLA-G protein expression exhibited spatio-temporal changes, which located in the extravillous trophoblast (EVT) and was higher in the placenta of the first and second trimesters while lower in the third trimester (P<0.01). CONCLUSION: HLA-G protein expression in different stages of pregnancy and different trophoblasts may be related to the controlled invasion of the trophoblast.
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